melanin is believed to protect the eye by trapping metals and free
radicals. The paper shows
that this unconfirmed mechanism is a rather fortuitous irreversible
molecular accident, which at
times may prove itself deleterious.
often leads to deafness in animals, indicating a genetic correlation.
These two conditions
appear to be correlated at a molecular level to eye/ ear pigmentation
and suggest verifying this
hypothesis in normal and albino human individuals.
and ocular melanin are chemically different. However, they are both
involved in light
absorption/dissipation. The black particle structure (melanin cage) is
believed to be fundamental to
this process because there is a common bioelectric mechanism. The latter
is worth of further
It is also proposed checking how ocular melanin dissipates the excessive
light (as heat or as current?). It has been claimed that inner ear
melanin mutes acoustic waves.
paper suggests investigating the underlying mechanism and also studying
pigment is bio-electrically involved in audio logy.
to numerous authors, Substantia
nigra melanin is only biological garbage. This view is
rejected, and it is stressed that intracellular melanogenesis is a
fundamental and genetically
controlled physiological process.
has been repeatedly claimed that the binding of iron, heavy metals, free
radicals and harmful
chemicals by substantia nigra melanin
is fundamental to body detoxification/protection.
such irreversible and generic binding mechanisms have no physiological
is suggested the alternative that, substantia
nigra melanin acts as semiconductor, transmitting and
modulating nervous impulses, in a
reversible way. In fact, substantia nigra melanin is absent or
significantly scarce in two conditions of life in which the coordination
of movement is either
inefficient (newborn babies) or strongly compromised (Parkinson).
check this assumption, further investigation of
nucleus caudatus, putamen, globus pallidus,
nigra pars compacta and
reticulata, nucleus hypothalamicus is recommended .